The National Institutes of Health will award up to $64 million over five years to encourage exploration of exceptionally innovative and original research ideas that have the potential for extraordinary impact.

The purpose of this Notice is to alert applicants that the NIH will hold a pre-application informational meeting for Request for Applications RFA-RM-10-011 - Knockout Mouse Phenotyping, RFA-RM-10-012 - Knockout Mouse Project Database, and RFA-RM-10-013 - Knockout Mouse Production and Cryopreservation.

The National Institutes of Health will award $9.4 million over three years to support four research projects in regulatory science. This research is conducted in partnership with the U.S. Food and Drug Administration, which will contribute approximately $950,000.

This FOA issued by the Office of Strategic Coordination, Office of the Director, National Institutes of Health, solicits grant applications from institutions/ organizations that propose to perform broad phenotyping of the International Knockout Mouse Consortium's (IKMC) mutant mice.

This FOA issued by the Office of Strategic Coordination, Office of the Director, National Institutes of Health, solicits grant applications from institutions/ organizations that propose to develop and implement a Data Coordination Center and Database (DCCDB) as part of the Knockout Mouse Phenotyping Project (KOMP2).

This FOA issued by the Office of Strategic Coordination, National Institutes of Health, solicits grant applications from institutions/ organizations that propose to convert the International Knockout Mouse Consortium's knockout embryonic stem (ES) cell libraries, into mice, perform quality control (QC) on the imported materials and subsequent products, cooperatively send the mice to the successful grantees under RFA-RM-10-011 for phenotyping, and cryopreserve germplasm of those mice and send aliquots to the KOMP repository.

The purpose of this Notice is to highlight three corrections to the application instructions in the FOA for the 2011 NIH Director's Pioneer Award.

The purpose of this Notice is to highlight three corrections to the application instructions in the FOA for the 2011 NIH Director's New Innovator Award.

An international study led by biologists and neuroscientists from the University of Pennsylvania has identified a new genetic risk factor for amyotrophic lateral sclerosis, commonly known as ALS or Lou Gehrig's disease.

Chemists and engineers at Harvard University have fashioned nanowires into a new type of V-shaped transistor small enough to be used for sensitive probing of the interior of cells.